Greetings from the ACTO chairperson

Akihiro Shimosaka

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Greetings from the editor

Yen Hua Huang

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Preface 2025 ACTO Annual Congress in Singapore

Mickey BC Koh

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Current landscape of cell and gene therapy in Singapore

Eddie Tan and Mickey BC Koh

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The symphony of time: how circadian rhythm shapes life

Chen-Kung Chou

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From circadian rhythm to primary ovarian insufficiency: a stem cell-based therapeutic perspective

Tony Yu-Xiu Lin, Thai-Yen Ling

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The double-edged niche: regulatory mechanisms in skin stem cells and cancer

Pham, T. T. Q. and Rita YH Huang

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APSEV spotlight: illuminating the next frontier in regenerative nanomedicine

Jui-Chien Hsing

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Harnessing the Tumor Microenvironment: Therapeutic Approaches to Modulate Cancer-Associated Fibroblasts

Dede Renovaldi, Yen-Hua Huang

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From Lab to Therapy: Unraveling Therapeutic Potentials of Functional Engineered Extracellular Vesicles

Joseph Wangisani Chisaka

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Role of Exosomes in Cancer: Molecular Mediator of Oncogenic Signaling and Microenvironmental Modulation

Vijetha Karen Kitchley