Tag: science
-
Overcoming manufacturing bottlenecks in cell and gene therapy: The emergence of the intelligent development and manufacturing organization (IDMO) model in Asia
Yu-Hsiang Chang, Ph.D.Chief Executive Officer (CEO), Locus Cell Co., Ltd. Abstract The clinical efficacy of Chimeric Antigen Receptor T-cell (CAR-T) therapies has irrevocably transformed the landscape of oncology and personalized medicine. Despite these groundbreaking clinical successes, the broad accessibility of these advanced therapies is severely limited by traditional manufacturing paradigms. High production costs, reliance on…
-
From Formosa to the world: leading the new era of regenerative medicine and cellular therapy in Taiwan
Dr. Chen-Chie Wang, MD., Ph.D.President of Formosa Association of Regenerative Medicine (FARM)Director of Department of Orthopedic Surgery, Taipei Tzu Chi Hospital, New Taipei City, TaiwanDepartment of Orthopedics, School of Medicine, Hualien Tzu Chi University, Hualien, Taiwan Regenerative medicine has rapidly evolved from experimental concepts into a transformative force in standard clinical care, ushering in a new…
-
Taiwan Association for Cellular Therapy (TACT)
April 29, 2026 The Taiwan Association for Cellular Therapy (TACT; https://www.celltherapy.org.tw/) was founded in 2014 with the mission of promoting cross-sector collaboration among industry, government, academia, medical institutions, and research communities in the field of cellular therapy. The Association is dedicated to advancing cell therapy science, technology, education, clinical translation, industrial development, and the establishment and refinement…
-
Therapeutic Potentials of Induced Pluripotent and Mesenchymal Stem Cell-Derived Exosomes
Vijetha Karen Kitchley, M.Sc.Editorial Office, The ACTO TimesInternational PhD Program in Cell Therapy & Regenerative Medicine, Taipei Medical University, Taiwan Introduction Mesenchymal stem cells (MSCs) have long been at the forefront of regenerative medicine due to their multipotency and immunomodulatory properties[1, 2]. However, direct stem cell transplantation is often limited by challenges such as donor-to-donor…
-
iPSC-derived cardiac cell sheets for heart regeneration: Progress towards clinical translation
Yuan-Yuan Cheng, Ph.D.International Ph.D. Program in Cell Therapy and Regenerative Medicine,College of Medicine, Taipei Medical University, Taiwan Abstract Background Heart disease remains the second leading cause of death worldwide. Currently, heart transplantation is considered the only definitive treatment for severe heart failure due to the poor heart regeneration after injury. Adult cardiomyocytes lose their proliferative…
-
The 20-year journey of induced pluripotent stem cells (iPSCs) in regenerative medicine
Tzu-Yu Chen, Yu-Xiu Lin, & Thai-Yen Ling, Ph.D.Graduate Institute of Pharmacology, College of MedicineNational Taiwan University, Taipei, Taiwan Human induced pluripotent stem cells (iPSCs) are pluripotent stem cells generated through the reprogramming of differentiated somatic cells into an embryonic stem cell-like state via the ectopic expression of defined transcription factors. Due to their unlimited self-renewal capability…
-
Cell and gene therapy in Vietnam: between scientific momentum and regulatory maturation
Duy-Cuong Le, MD, Ph.D.Laboratory, Vinmec Riverside, Vinmec Healthcare System, VietnamCollege of Health Sciences, VinUniversity, Hanoi, Vietnam Introduction Cell and gene therapy (CGT) is reshaping modern medicine by enabling interventions at the level of cellular function and genetic programming. From hematologic malignancies to rare inherited disorders, these therapies have shifted from experimental promise to clinical reality…
-
Current picture in cell and stem cell therapy research in Vietnam
Trang Thao Quoc Pham, MD, Ph.DGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, TaiwanDept. of Dermatology, Faculty of Medicine, University of Medicine & Pharmacy, Ho Chi Minh City, Vietnam Introduction In recent years, cell and gene therapy (CGT) has experienced remarkable growth in Vietnam, mirroring global innovation while leveraging local scientific expertise.…
-
The university perspective in cell & gene therapy in Indonesia: landscape, challenges, progress, and a strategic vision for breakthrough
Ova Emilia, MD, Ph.D., Dian K. Nurputra, MD, Ph.D., & Rusdy Ghazali Malueka, MD, Ph.D.Univesitas Gadjah Mada, Yogyakarta, Indonesia Introduction: A Nation at the Inflection Point As the ACTO Annual Meeting 2026 convenes in Jakarta, a fitting recognition of Indonesia’s growing prominence in the Asian cellular therapy landscape, the country finds itself at a defining…
-
Advancing cell-based and emerging CGT ecosystem in Indonesia: the strategic role of the Indonesian Stem Cell Association (ASPI)
Amin Soebandrio1, Rahyussalim2, Cynthia Retna Sartika1,2, Rusdy Ghazali Malueka1,2,Isabella Kurnia Liem2, Angliana Chouw2, Rima Haifa2,Retina Syhallala Askandar2, Blessari Tesalonika Woran2 1Stem Cell Committee, Ministry of Health of Indonesia, Indonesia, 2Indonesian Stem Cell Association, Indonesia Abstract Cell and gene therapy (CGT) has emerged as an important field of modern medicine, integrating regenerative medicine, stem cell science,…
THE ACTO TIMES 