Tag: cancer
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Developing Gene Therapy Capacity in Thailand: Clinical, Economic, and Regulatory Perspectives
Kitipong Uaesoontrachoon1, Parin Rattananon1, Usanarat Anurathapan1,2, Suradej Hongeng11Genepeutic Bio, Co. Ltd., Bangkok, Thailand2Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Abstract Gene therapy has emerged as a transformative therapeutic modality for genetic and hematologic diseases. In Thailand, where hemoglobinopathies and pediatric acute lymphoblastic leukemia (ALL) represent significant public health burdens, the development of domestic…
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Beyond Carcinogenesis: Connecting Nicotine Signaling with Cancer Stemness and Metastatic Progression in Triple-Negative Breast Cancer
Yung-Che Kuo, Ph.D. 1 & Yen-Hua Huang, Ph.D. 1,2,31 TMU Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan.2 Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan3 International Ph.D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical…
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Indonesia Cell & Gene Therapy (CGT) 2026 Update
Josephine Diony Nanda, M.D., Ph.D.Department of Parasitology, Faculty of Medicine, Public Health, & Nursing (FKKMK), Universitas Gadjah Mada Cell and gene therapy (CGT) has emerged as one of the most transformative innovations in modern medicine, offering new hope for patients with previously untreatable conditions. In Indonesia, the journey of CGT is still in its early…
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Role of Exosomes in Cancer: Molecular Mediator of Oncogenic Signaling and Microenvironmental Modulation
Mechanistic Overview of the Immune Evasion, Angiogenesis and Diagnostic Applications in Cancer Vijetha Karen Kitchley International PhD program in cell therapy and regenerative medicine, Taipei Medical University Exosomes are nano-sized extracellular vesicles (30–150 nm) encapsulated by a phospholipid bilayer and secreted by both prokaryotic and eukaryotic cells to facilitate intercellular communication and molecular signaling (Fig.…
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Preface 2025 ACTO Annual Congress in Singapore
It is with immense pleasure that I welcome all invited speakers, delegates and honoured guests to the 2025 Asian Cellular Therapy Organisation (ACTO) congress held in Singapore. This congress is happening at a pivotal moment in the fast-evolving field of cell and gene therapy. There are bewilderingly rapid developments in diverse areas from approved gene therapy…
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The double-edged niche: regulatory mechanisms in skin stem cells and cancer
Pham, T. T. Q. and Rita YH HuangTaipei Medical University, Taipei Human skin represents one of nature’s most sophisticated examples of tissue homeostasis, functioning as an intricate biological system that seamlessly balances protection, regeneration, and adaptive responses to environmental stressors. Normal skin homeostasis operates through a carefully orchestrated cellular hierarchy, where skin stem cells (SSCs)…
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Current landscape of cell and gene therapy in Singapore
Eddie Tan1 and Mickey BC Koh2 Singapore has emerged as a key player in the cell and gene therapy (CGT) sector in Asia, with significant developments in infrastructure, regulatory frameworks, and clinical advancements. The country has strategically positioned itself to become a regional hub for CGT research, development, and clinical applications through substantial investments, purpose-built facilities,…
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