Category: Uncategorized
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From circadian rhythm to primary ovarian insufficiency: a stem cell-based therapeutic perspective
Tony Yu-Xiu Lin, Thai-Yen LingDepartment and Graduate Institute of Pharmacology, National Taiwan University, College of Medicine, Taipei, Taiwan From the earliest stages of life on Earth, organisms have adapted to the predictable cycles of day and night. This evolutionary adaptation has given rise to the circadian rhythm, an intrinsic 24‑hour biological cycle regulating physiological activities…
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The double-edged niche: regulatory mechanisms in skin stem cells and cancer
Pham, T. T. Q. and Rita YH HuangTaipei Medical University, Taipei Human skin represents one of nature’s most sophisticated examples of tissue homeostasis, functioning as an intricate biological system that seamlessly balances protection, regeneration, and adaptive responses to environmental stressors. Normal skin homeostasis operates through a carefully orchestrated cellular hierarchy, where skin stem cells (SSCs)…
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The symphony of time: how circadian rhythms shape life and medicine
Chen-Kung ChouDepartment of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University From the first flicker of life on Earth, the cycle of day and night has been an inescapable backdrop—steady, rhythmic, and profoundly influential. As life evolved, it began not only to respond to this 24-hour cycle but to anticipate…
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Current landscape of cell and gene therapy in Singapore
Eddie Tan1 and Mickey BC Koh2 Singapore has emerged as a key player in the cell and gene therapy (CGT) sector in Asia, with significant developments in infrastructure, regulatory frameworks, and clinical advancements. The country has strategically positioned itself to become a regional hub for CGT research, development, and clinical applications through substantial investments, purpose-built facilities,…
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Greetings from the editor
THE ACTO TIMES: 2025 SUMMER EDITION Dear ACTO Members and Readers of The ACTO Times, I am excited to present the 2025 Summer Edition of The ACTO Times, which highlights the upcoming 2025 Singapore ACTO Annual Meeting and recent advances in Asian cell and gene therapy (CGT). As of 2025, over 100 CGT products have…
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Greetings from the ACTO chairperson
The ACTO times: 2025 summer edition Akihiro Shimosaka Dear ACTO members, We are glad to share the Summer edition of The ACTO Times 2025, the second annual electronic magazine for ACTO’s global connection in cell and gene therapy (CGT). The Asian Cellular Therapy Organization (ACTO) was founded in 2010 to support Asia’s scientific community. Established by experts from all over Asia, ACTO serves for…
THE ACTO TIMES 