Tag: nutrition
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Developing Gene Therapy Capacity in Thailand: Clinical, Economic, and Regulatory Perspectives
Kitipong Uaesoontrachoon1, Parin Rattananon1, Usanarat Anurathapan1,2, Suradej Hongeng11Genepeutic Bio, Co. Ltd., Bangkok, Thailand2Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Abstract Gene therapy has emerged as a transformative therapeutic modality for genetic and hematologic diseases. In Thailand, where hemoglobinopathies and pediatric acute lymphoblastic leukemia (ALL) represent significant public health burdens, the development of domestic…
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Beyond Carcinogenesis: Connecting Nicotine Signaling with Cancer Stemness and Metastatic Progression in Triple-Negative Breast Cancer
Yung-Che Kuo, Ph.D. 1 & Yen-Hua Huang, Ph.D. 1,2,31 TMU Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan.2 Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan3 International Ph.D. Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical…
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Regulation of Cell and Gene Therapy (CGT) in Indonesia: Perspective of BPOM
D. Renovaldi, M.ScInternational Ph.D Program in Medicine, Taipei Medical University Introduction Cell and Gene Therapy (CGT) represents a rapidly advancing field in biomedical science, offering innovative treatment strategies for diseases that were previously difficult or impossible to treat. These therapies involve the modification or administration of living cells or genetic material to restore normal biological…
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The New Era of Regenerative Medicine: Synergistic Development of Innovative Therapies and the National Health Insurance System
Lian-Yu Chen, M.D.,Ph.D.Director-GeneralNational Health Insurance Administration, Taiwan With the rapid development of regenerative medicine, innovative therapies are gradually transforming disease treatment paradigms. To address high-cost therapies associated with significant uncertainty, Taiwan’s National Health Insurance (NHI) has established corresponding reimbursement and management mechanisms. Cell and Gene Therapy: Opening a New Era of Medicine In recent years,…
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Ushering in a new regulatory era for regenerative medicine in Taiwan
Dr. Chih-Kang Chiang, MD., Ph.D.Director-GeneralTaiwan Food and Drug AdministrationMinistry of Health and WelfareTaiwan Due to rapid development of biotechnology in recent years, the field of regenerative medicine has attracted considerable attention. Regenerative medicine related regulations have been established in several countries to ensure the quality, safety and efficacy of innovative treatments. Considering the diversity of…
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Role of Exosomes in Cancer: Molecular Mediator of Oncogenic Signaling and Microenvironmental Modulation
Mechanistic Overview of the Immune Evasion, Angiogenesis and Diagnostic Applications in Cancer Vijetha Karen Kitchley International PhD program in cell therapy and regenerative medicine, Taipei Medical University Exosomes are nano-sized extracellular vesicles (30–150 nm) encapsulated by a phospholipid bilayer and secreted by both prokaryotic and eukaryotic cells to facilitate intercellular communication and molecular signaling (Fig.…
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Preface 2025 ACTO Annual Congress in Singapore
It is with immense pleasure that I welcome all invited speakers, delegates and honoured guests to the 2025 Asian Cellular Therapy Organisation (ACTO) congress held in Singapore. This congress is happening at a pivotal moment in the fast-evolving field of cell and gene therapy. There are bewilderingly rapid developments in diverse areas from approved gene therapy…
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The double-edged niche: regulatory mechanisms in skin stem cells and cancer
Pham, T. T. Q. and Rita YH HuangTaipei Medical University, Taipei Human skin represents one of nature’s most sophisticated examples of tissue homeostasis, functioning as an intricate biological system that seamlessly balances protection, regeneration, and adaptive responses to environmental stressors. Normal skin homeostasis operates through a carefully orchestrated cellular hierarchy, where skin stem cells (SSCs)…